Article
Functional variation in VEGF is not associated with type 2 diabetes in a United Kingdom Caucasian population.
JOP : Journal of the pancreas - 9 May 2006
Freathy Rachel M, Weedon Michael N, Shields Beverley, Hitman Graham A, Walker Mark, McCarthy Mark I, Hattersley Andrew T, Frayling Timothy M
Abstract excerpt
CONTEXT: Vascular endothelial growth factor (VEGF) is important for pancreatic beta cell development and function. Common variation in the VEGF gene is associated with altered serum concentrations of VEGF and with several diseases, but its role in type 2 diabetes is not known. The single nucleotide polymorphisms C-2578A (rs699947), G-1154A (rs1570360) and G-634C (rs2010963) in the 5'-region of VEGF are associated...
Read the complete abstract on PubMed