Article
K469E polymorphism of the intracellular adhesion molecule 1 gene is associated with proliferative diabetic retinopathy in Caucasians with type 2 diabetes.
Clinical & experimental ophthalmology - 1 Jul 2008
Petrovic Mojca Globocnik, Osredkar Josko, Saraga-Babić Mirna, Petrovic Daniel
Abstract excerpt
BACKGROUND: In proliferative diabetic retinopathy (PDR) increased levels of cytokines, inflammatory cells and angiogenic factors are present.These factors increase the expression of cellular adhesion molecules (CAMs)The objective of this study was to investigate the association between the polymorphisms of the ICAM-1 gene (K469E, G241A) and the development of PDR among patients with type 2 diabetes in the...
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