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Platelet-endothelial cell adhesion molecule-1 gene polymorphism and its soluble level are associated with severe coronary artery stenosis in Chinese Singaporean.

Clinical biochemistry - 1 Dec 2004

Wei Heming, Fang Lu, Chowdhury Sanual H, Gong Nanling, Xiong Zhuowei, Song Jie, Mak Koon Hou, Wu Saizhu, Koay Evelyn, Sethi Sunil, Lim Yean Leng, Chatterjee Subroto

Abstract excerpt

OBJECTIVES: Platelet-endothelial cell adhesion molecule-1 (PECAM-1) mediates the transendothelial migration of circulating leukocytes, a characteristic change in vascular inflammation leading to atherosclerotic plaque development. We hypothesized that genetic variation and soluble level of PECAM-1 could be associated with coronary artery disease (CAD). DESIGN AND METHODS: We analyzed two single nucleotide...

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Identifiers

PMID: 15589815
DOI: 10.1016/j.clinbiochem.2004.08.006

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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