Article
The fub-1 mutation blocks initial myofibril formation in zebrafish muscle pioneer cells.
Developmental biology - 1 Nov 1991
Felsenfeld A L, Curry M, Kimmel C B
Abstract excerpt
The earliest muscle in zebrafish arises from iterated sets of two to six cells in each somite, the muscle pioneers (MP). MP develop synchronously in young trunk myotomes adjacent to the notochord, precisely where the horizontal myoseptum will form. They elongate without cell fusion and differentiate hours earlier than surrounding cells, thus providing a simple and accessible system for in vivo study of myogenesis...
Topics
- Actins
- Animals
- Cell Differentiation
- Culture Techniques
- Microscopy, Electron
- Muscles
- Mutation
- Myofibrils
- Zebrafish