Article
Origin and Evolution of the Sponge Aggregation Factor Gene Family.
Molecular biology and evolution - 1 May 2017
Grice Laura F, Gauthier Marie E A, Roper Kathrein E, Fernàndez-Busquets Xavier, Degnan Sandie M, Degnan Bernard M
Abstract excerpt
Although discriminating self from nonself is a cardinal animal trait, metazoan allorecognition genes do not appear to be homologous. Here, we characterize the Aggregation Factor (AF) gene family, which encodes putative allorecognition factors in the demosponge Amphimedon queenslandica, and trace its evolution across 24 sponge (Porifera) species. The AF locus in Amphimedon is comprised of a cluster of five similar...
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