Article
Molecular evolution and in vitro characterization of Botryllus histocompatibility factor.
Immunogenetics - 1 Oct 2015
Taketa Daryl A, Nydam Marie L, Langenbacher Adam D, Rodriguez Delany, Sanders Erin, De Tomaso Anthony W
Abstract excerpt
Botryllus schlosseri is a colonial ascidian with a natural ability to anastomose with another colony to form a vascular and hematopoietic chimera. In order to fuse, two individuals must share at least one allele at the highly polymorphic fuhc locus. Otherwise, a blood-based inflammatory response will occur resulting in a melanin scar at the sites of interaction. The single-locus genetic control of allorecognition...
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