Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Stepwise addition of genetic changes correlated with histological change from "well-differentiated" to "sarcomatoid" phenotypes: a case report.

BMC cancer - 19 Jan 2017

Goto Taichiro, Hirotsu Yosuke, Mochizuki Hitoshi, Nakagomi Takahiro, Oyama Toshio, Amemiya Kenji, Omata Masao

Abstract excerpt

BACKGROUND: Sarcomatoid cancer is defined by the World Health Organization as a category of non-small cell lung cancers with sarcoma or sarcoma-like differentiation. They are characterized by poor prognosis and resistance to conventional chemotherapy. However, the mutational profile of sarcomatoid cancer remains yet to be elucidated. Sarcomatoid cancers are usually biphasic tumors composed of carcinomatous and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lung Neoplasms

Share to Mutation

Share to Neoplasm Staging

Share to Phenotype

Share to Prognosis

Share to Sarcoma

Source

Open in PubMed Open full text

Identifiers

PMID: 28103823
DOI: 10.1186/s12885-017-3059-1
PMCID: PMC5248474

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Stepwise addition of genetic changes correlated with histological change from "well-differentiated" to "sarcomatoid" phenotypes: a case report.PMID 28103823Read ↗

New therapeutic targets for pulmonary sarcomatoid carcinomas based on their genomic and phylogenetic profilesSemantic proximity Read ↗

Rare transformation from lung adenocarcinoma to sarcomatoid carcinoma mediates resistance to inhibitors targeting different driver oncogenesSemantic proximity Read ↗

Histologic Changes in Non-Small Cell Lung Cancer under Various Treatments: A Comparison of Histology and Mutation Status in Serial Samples.Semantic proximity Read ↗

Analysis of molecular pathologic and clinical features of 36 patients with pulmonary sarcomatoid carcinoma.Semantic proximity Read ↗

Clinicopathological and molecular features of non-small cell lung cancer without TKI therapy that transforms into small-cell lung cancerSemantic proximity Read ↗

[Pulmonary sarcomatoid carcinoma:report of three cases].Semantic proximity Read ↗

Analysis of molecular pathologic and clinical features of 36 patients with pulmonary sarcomatoid carcinomaSemantic proximity Read ↗

Genomic Landscape of Pulmonary Sarcomatoid Carcinoma.Semantic proximity Read ↗

Molecular and expressional characterization of tumor heterogeneity in pulmonary carcinosarcoma.Semantic proximity Read ↗

Morphologic-Molecular Transformation of Oncogene Addicted Non-Small Cell Lung Cancer.Semantic proximity Read ↗

Deep Sequencing Analysis Reveals That KRAS Mutation Is a Marker of Poor Prognosis in Patients with Pulmonary Sarcomatoid Carcinoma.Semantic proximity Read ↗

Histological transformation after acquired resistance to epidermal growth factor tyrosine kinase inhibitors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.