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Article

Molecular and expressional characterization of tumor heterogeneity in pulmonary carcinosarcoma.

Molecular carcinogenesis - 1 Oct 2022

Ohtaki Yoichi, Kawabata-Iwakawa Reika, Nobusawa Sumihito, Goto Yusuke, Shimizu Kimihiro, Yajima Toshiki, Nakazawa Seshiru, Kawatani Natsuko, Yoshida Yuka, Sano Takaaki, Shirabe Ken

Abstract excerpt

The genetic concordance and heterogeneity of the two components of pulmonary carcinosarcoma (PCS), carcinoma, and sarcoma, have not been fully elucidated because of its rare occurrence. We performed targeted sequencing of the carcinoma and sarcoma components of four PCSs to identify genetic similarities and differences. Formalin-fixed paraffin-embedded tissue samples were macroscopically or microscopically...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35848137
DOI: 10.1002/mc.23448

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