Article
Genome-wide association study using the ethnicity-specific Japonica array: identification of new susceptibility loci for cold medicine-related Stevens-Johnson syndrome with severe ocular complications.
Journal of human genetics - 1 Apr 2017
Ueta Mayumi, Sawai Hiromi, Shingaki Ryosei, Kawai Yusuke, Sotozono Chie, Kojima Kaname, Yoon Kyung-Chul, Kim Mee Kum, Seo Kyoung Yul, Joo Choun-Ki, Nagasaki Masao, Kinoshita Shigeru, Tokunaga Katsushi
Abstract excerpt
A genome-wide association study (GWAS) for cold medicine-related Stevens-Johnson syndrome (CM-SJS) with severe ocular complications (SOC) was performed in a Japanese population. A recently developed ethnicity-specific array with genome-wide imputation that was based on the whole-genome sequences of 1070 unrelated Japanese individuals was used. Validation analysis with additional samples from Japanese individuals...
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