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The PTPN14 Tumor Suppressor Is a Degradation Target of Human Papillomavirus E7

18 Jan 2017

Abstract excerpt

ABSTRACT Activation of signaling pathways ensuring cell growth is essential for the proliferative competence of human papillomavirus (HPV)-infected cells. Tyrosine kinases and phosphatases are key regulators of cellular growth control pathways. A recently identified potential cellular target of HPV E7 is the cytoplasmic protein tyrosine phosphatase PTPN14, which is a potential tumor suppressor and is linked to...

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PMID: 28100625
DOI: 10.1128/jvi.00057-17

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