Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

M2-like macrophages induce colon cancer cell invasion via matrix metalloproteinases.

Journal of cellular physiology - 1 Dec 2017

Vinnakota Katyayni, Zhang Yuan, Selvanesan Benson Chellakkan, Topi Geriolda, Salim Tavga, Sand-Dejmek Janna, Jönsson Gunilla, Sjölander Anita

Abstract excerpt

The inflammatory milieu plays an important role in colon cancer development and progression. Previously, we have shown that tumor-associated macrophages (TAMs), an important component of the tumor microenvironment, are enriched in tumors compared with normal tissue and confer a poorer prognosis. In the present study, we found that matrix metallopeptidase-9 (MMP-9), which degrades extracellular matrix proteins,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colonic Neoplasms
Share to Culture Media, Conditioned

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epithelial-Mesenchymal Transition

Share to Matrix Metalloproteinase 9

Share to Matrix Metalloproteinase Inhibitors

Share to Mice, Nude

Share to Paracrine Communication

Share to Tumor Microenvironment

Source

Identifiers

PMID: 28098359
DOI: 10.1002/jcp.25808

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

M2-like macrophages induce colon cancer cell invasion via matrix metalloproteinases.PMID 28098359Read ↗

miR-19–Mediated Inhibition of Transglutaminase-2 Leads to Enhanced Invasion and Metastasis in Colorectal CancerSemantic proximity Read ↗

HMGA2 facilitates colorectal cancer progression via STAT3-mediated tumor-associated macrophage recruitmentSemantic proximity Read ↗

M2 Macrophage-Derived Exosomal miR-590-3p Attenuates DSS-Induced Mucosal Damage and Promotes Epithelial Repair via the LATS1/YAP/ β-Catenin Signalling Axis.Semantic proximity Read ↗

Promotion of Tumor Growth by ADAMTS4 in Colorectal Cancer: Focused on Macrophages.Semantic proximity Read ↗

Extracellular Oncosomes Rich in Moonlighting Metalloproteinase (MMP3) Are Transmissive, Pro-Tumorigenic, and Induces Cellular Communication Network Factor 2 (CCN2/CTGF): CRISPR against CancerSemantic proximity Read ↗

Conditioned media from macrophages of M1, but not M2 phenotype, inhibit the proliferation of the colon cancer cell lines HT-29 and CACO-2.Semantic proximity Read ↗

COX-2 inhibition alters the phenotype of tumor-associated macrophages from M2 to M1 in ApcMin/+ mouse polyps.Semantic proximity Read ↗

MAPKAP Kinase-2 Drives Expression of Angiogenic Factors by Tumor-Associated Macrophages in a Model of Inflammation-Induced Colon Cancer.Semantic proximity Read ↗

Tumour necrosis factor alpha confers an invasive, transformed phenotype on mammary epithelial cells.Semantic proximity Read ↗

In vitro evaluation of inhibitory effect of nuclear factor-kappaB activity by small interfering RNA on pro-tumor characteristics of M2-like macrophages.Semantic proximity Read ↗

Enterococcus faecalis promotes a migratory and invasive phenotype in colon cancer cells.Semantic proximity Read ↗

Critical role of N-cadherin in myofibroblast invasion and migration in vitro stimulated by colon-cancer-cell-derived TGF-beta or wounding.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.