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Article

Critical role of N-cadherin in myofibroblast invasion and migration in vitro stimulated by colon-cancer-cell-derived TGF-beta or wounding.

Journal of cell science - 15 Sept 2004

De Wever Olivier, Westbroek Wendy, Verloes An, Bloemen Nele, Bracke Marc, Gespach Christian, Bruyneel Erik, Mareel Marc

Abstract excerpt

Invasion of stromal host cells, such as myofibroblasts, into the epithelial cancer compartment may precede epithelial cancer invasion into the stroma. We investigated how colon cancer-derived myofibroblasts invade extracellular matrices in vitro in the presence of colon cancer cells. Myofibroblast spheroids invade collagen type I in a stellate pattern to form a dendritic network of extensions upon co-culture with...

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Identifiers

PMID: 15331629
DOI: 10.1242/jcs.01322

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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