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Article

Promotion of Tumor Growth by ADAMTS4 in Colorectal Cancer: Focused on Macrophages.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2018

Chen Jianjun, Luo Yang, Zhou Yong, Qin Shaolan, Qiu Yier, Cui Ran, Yu Minhao, Qin Jun, Zhong Ming

Abstract excerpt

BACKGROUND/AIMS: ADAMTSs (A disintegrin and metalloprotease domains with thrombospondins motifs) are a family of extracellular proteases that have been related to both oncogenic and tumor-suppressive functions. The aim of the present study was to investigate: 1) the mutation, copy-number alterations, and expression profile of ADAMTSs in colorectal cancer and 2) whether ADAMTSs participate in colorectal cancer...

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Identifiers

PMID: 29694979
DOI: 10.1159/000489245

Genes

ADAMTS4

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