Article
Epigenetic modifications at DMRs of placental genes are subjected to variations in normal gestation, pathological conditions and folate supplementation.
Scientific reports - 18 Jan 2017
Rahat Beenish, Mahajan Aatish, Bagga Rashmi, Hamid Abid, Kaur Jyotdeep
Abstract excerpt
Invasive placentation and cancer development shares many similar molecular and epigenetic pathways. Paternally expressed, growth promoting genes (SNRPN, PEG10 and MEST) which are known to play crucial role in tumorogenesis, are not well studied during placentation. This study reports for the first time of the impact of gestational-age, pathological conditions and folic acid supplementation on dynamic nature of...
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