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Article

Widespread DNA hypomethylation at gene enhancer regions in placentas associated with early-onset pre-eclampsia

13 Jun 2013

Abstract excerpt

Pre-eclampsia is a serious complication of pregnancy that can affect both maternal and fetal outcomes. Early-onset pre-eclampsia (EOPET) is a severe form of pre-eclampsia that is associated with altered physiological characteristics and gene expression in the placenta. DNA methylation is a relatively stable epigenetic modification to DNA that can reflect gene expression, and can provide insight into the...

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Share to Epigenetics and DNA Methylation
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PMID: 23770704
DOI: 10.1093/molehr/gat044

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