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Article

The Role of Epigenetics in Placental Development and the Etiology of Preeclampsia

11 Jun 2019

Abstract excerpt

In this review, we comprehensively present the function of epigenetic regulations in normal placental development as well as in a prominent disease of placental origin, preeclampsia (PE). We describe current progress concerning the impact of DNA methylation, non-coding RNA (with a special emphasis on long non-coding RNA (lncRNA) and microRNA (miRNA)) and more marginally histone post-translational modifications,...

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PMID: 31212604
DOI: 10.3390/ijms20112837

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