Article
Aryl hydrocarbon receptor signaling involved in the invasiveness of LNCaP cells.
Human cell - 1 Apr 2017
Ide Hisamitsu, Lu Yan, Yu Jingsong, Noguchi Takahiro, Kanayama Mayuko, Muto Satoru, Yamaguchi Raizo, Kawato Suguru, Horie Shigeo
Abstract excerpt
There is now mounting evidence that the aryl hydrocarbon receptor (AhR) plays an important role in physiologic responses such as development, cell cycle regulation, immune function and also malignant transformation in various tissues. The strong nuclear AhR expression is observed in the invasive phenotype, and an elevated nuclear AhR expression is associated with a poor prognosis of human prostate cancer. On the...
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