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Article

Fog signaling is dispensable for Drosophila tracheal invagination.

Developmental biology - 1 Jul 2026

Vishwakarma Vishakha, Le Thao Phuong, Obadofin Deborah, Lee Cailyn J, Wheat Margaret A, Chung SeYeon

Abstract excerpt

Folded gastrulation (Fog), a secreted ligand for a G protein-coupled receptor (GPCR), is a key regulator of cell shape changes during epithelial morphogenesis. During Drosophila embryogenesis, fog is expressed in multiple invaginating tissues, including the mesoderm, salivary gland, and trachea. In the mesoderm and salivary gland, Fog signaling coordinates apical constriction through Rho kinase (Rok)-mediated...

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Drosophila
Drosophila melanogaster
Drosophila Proteins
Embryo, Nonmammalian
Morphogenesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

rho-Associated Kinases

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PMID: 41967745
DOI: 10.1016/j.ydbio.2026.04.002
PMCID: PMC13110720

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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