Article
Mechanical signals trigger Myosin II redistribution and mesoderm invagination in Drosophila embryos.
Science signaling - 14 Apr 2009
Pouille Philippe-Alexandre, Ahmadi Padra, Brunet Anne-Christine, Farge Emmanuel
Abstract excerpt
During Drosophila gastrulation, two waves of constriction occur in the apical ventral cells, leading to mesoderm invagination. The first constriction wave is a stochastic process mediated by the constriction of 40% of randomly positioned mesodermal cells and is controlled by the transcription factor Snail. The second constriction wave immediately follows and involves the other 60% of the mesodermal cells. The...
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