Article
The MTHFR C677T mutation is not a risk factor recognized for HBV-related HCC in a population with a high prevalence of this genetic marker.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Apr 2017
Jiao Xiaolei, Luo Ying, Yang Bin, Jing Li, Li Yayue, Liu Changzheng, Jing Xiang, Wang Fengmei, Wang Yijun, Du Zhi, Gao Yingtang
Abstract excerpt
BACKGROUND: Polymorphism of the methylenetetrahydrofolate reductase (MTHFR) gene can affect disease progression in HBV infection. However, the results from different reports are inconsistent. The aim of this study was to investigate the association between the MTHFR C677T polymorphism and the outcome of HBV infection in a Tianjin Han population. METHODS: TaqMan SNP genotyping was employed to determine the alleles...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.