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Article

Impact of methylene-tetrahydrofolate reductase gene C677T and A1298C polymorphisms as a risk factor for hepatitis B virus infection.

Nucleosides, nucleotides & nucleic acids - 1 Jan 2023

Karakus Nevin, Yigit Serbulent, Kocak Mustafa, Bozkurt Nihan, Duygu Fazilet

Abstract excerpt

Chronic hepatitis B infection caused by Hepatitis B virus (HBV), influences over two billion people worldwide despite having an effective vaccine. With a total prevalence of 4.57%, there are 3.3 million estimated HBV carriers in Türkiye. Methylene-tetrahydrofolate reductase (MTHFR) arrange folate metabolism through nucleic acid synthesis and DNA methylation. C677T (rs1801133, p.Ala222Val) and A1298C (rs1801131,...

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PMID: 36919686
DOI: 10.1080/15257770.2023.2187061

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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