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Article

Genetic Screening of WNT4 and WNT5B in Two Populations with Deviating Bone Mineral Densities.

Calcified tissue international - 1 Mar 2017

Hendrickx Gretl, Boudin Eveline, Steenackers Ellen, Nielsen Torben Leo, Andersen Marianne, Brixen Kim, Van Hul Wim

Abstract excerpt

A role for WNT4 and WNT5B in bone metabolism was indicated by genome-wide association studies (GWAS) and a Wnt4 knockout mouse model. The aim of this study was therefore to replicate and further investigate the causality between genetic variation in WNT4 and WNT5B and deviating bone mineral density (BMD) values. A WNT4 and WNT5B mutation screening was performed in patients with craniotubular hyperostosis using...

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Source

Identifiers

PMID: 28078366
DOI: 10.1007/s00223-016-0213-8

Genes

WNT4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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