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Article

Maturation strategies and limitations of induced pluripotent stem cell-derived cardiomyocytes.

Bioscience reports - 25 Jun 2021

Wu Peng, Deng Gang, Sai Xiyalatu, Guo Huiming, Huang Huanlei, Zhu Ping

Abstract excerpt

Induced pluripotent stem cells (iPSCs) have the ability to differentiate into cardiomyocytes (CMs). They are not only widely used in cardiac pharmacology screening, human heart disease modeling, and cell transplantation-based treatments, but also the most promising source of CMs for experimental and clinical applications. However, their use is largely restricted by the immature phenotype of structure and...

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Identifiers

PMID: 33057659
DOI: 10.1042/BSR20200833
PMCID: PMC8209171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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