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Article

Detecting APC Gene Mutations in Familial Adenomatous Polyposis (FAP).

Current protocols in human genetics - 11 Jan 2017

Nallamilli Babi Ramesh Reddy, Hegde Madhuri

Abstract excerpt

Hereditary forms of colorectal cancer (CRC) account for up to 5% of total cases. Familial adenomatous polyposis (FAP) is an autosomal dominant condition affecting nearly 1 in 5000 people and accounts for only about 1% of all CRCs. It is characterized by the progressive development of hundreds to thousands of adenomatous colon polyps. The gene associated with FAP (APC) contains 15 coding exons. The mutation...

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Source

Identifiers

PMID: 28075483
DOI: 10.1002/cphg.29

Genes

APC
FAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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