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Article

Genetic differences in familial adenomatous polyposis syndrome in a Hungarian population: A prospective single center study.

World journal of gastroenterology - 7 Jan 2026

Tóth Tibor, Bor Renáta, Nagy Dóra, Török Dóra, Molnár Tamás, Farkas Klaudia, Fábián Anna, Bősze Zsófia, Bálint Anita, Bacsur Péter, Resál Tamás, Szell Marta, Szepes Zoltán

Abstract excerpt

BACKGROUND: Familial adenomatous polyposis (FAP) is a disorder of autosomal dominant inheritance that is responsible for around 1% of colorectal cancer (CRC) cases. AIM: To determine the mutation profile of FAP-specific to the Hungarian population. METHODS: This prospective single-center study enrolled patients with clinically suspected FAP or attenuated FAP (aFAP). Whole-exome next-generation sequencing was...

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Identifiers

PMID: 41551532
DOI: 10.3748/wjg.v32.i1.110043
PMCID: PMC12809144

Genes

FAP
APC
CHEK2
MSH3
PIEZO1
POLE

Provenance

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