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Article

Brain Structure and Function Associated with Younger Adults in Growth Hormone Receptor-Deficient Humans.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Feb 2017

Nashiro Kaoru, Guevara-Aguirre Jaime, Braskie Meredith N, Hafzalla George W, Velasco Rico, Balasubramanian Priya, Wei Min, Thompson Paul M, Mather Mara, Nelson Marvin D, Guevara Alexandra, Teran Enrique, Longo Valter D

Abstract excerpt

Growth hormone receptor deficiency (GHRD) results in short stature, enhanced insulin sensitivity, and low circulating levels of insulin and insulin-like growth factor 1 (IGF-1). Previous studies in mice and humans suggested that GHRD has protective effects against age-related diseases, including cancer and diabetes. Whereas GHRD mice show improved age-dependent cognitive performance, the effect of GHRD on human...

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Identifiers

PMID: 28073935
DOI: 10.1523/JNEUROSCI.1929-16.2016
PMCID: PMC5320603

Genes

GHR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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