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Article

Use of whole genome analysis to identify shared genomic variants across breeds in canine mitral valve disease.

Human genetics - 1 Nov 2021

Williams Brian, Friedenberg Steven G, Keene Bruce W, Tou Sandy P, DeFrancesco Teresa C, Meurs Kathryn M

Abstract excerpt

Familial mitral valve prolapse in human beings has been associated with several genetic variants; however, in most cases, a known variant has not been identified. Dogs also have a naturally occurring form of familial mitral valve disease (MMVD) with similarities to the human disease. A shared genetic background and clinical phenotype of this disease in some dog breeds has indicated that the disease may share a...

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PMID: 34176051
DOI: 10.1007/s00439-021-02297-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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