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Article

Differential Contribution of Subunit Interfaces to α9α10 Nicotinic Acetylcholine Receptor Function.

Molecular pharmacology - 1 Mar 2017

Boffi Juan Carlos, Marcovich Irina, Gill-Thind JasKiran K, Corradi Jeremías, Collins Toby, Lipovsek María Marcela, Moglie Marcelo, Plazas Paola V, Craig Patricio O, Millar Neil S, Bouzat Cecilia, Elgoyhen Ana Belén

Abstract excerpt

Nicotinic acetylcholine receptors can be assembled from either homomeric or heteromeric pentameric subunit combinations. At the interface of the extracellular domains of adjacent subunits lies the acetylcholine binding site, composed of a principal component provided by one subunit and a complementary component of the adjacent subunit. Compared with neuronal nicotinic acetylcholine cholinergic receptors (nAChRs)...

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Identifiers

PMID: 28069778
DOI: 10.1124/mol.116.107482
PMCID: PMC5325082

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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