Article
C1q/TNF-related protein 1 prevents neointimal formation after arterial injury.
Atherosclerosis - 1 Feb 2017
Kanemura Noriyoshi, Shibata Rei, Ohashi Koji, Ogawa Hayato, Hiramatsu-Ito Mizuho, Enomoto Takashi, Yuasa Daisuke, Ito Masanori, Hayakawa Satoko, Otaka Naoya, Murohara Toyoaki, Ouchi Noriyuki
Abstract excerpt
BACKGROUND AND AIMS: Obesity contributes to the progression of vascular disorders. C1q/TNF-related protein (CTRP) 1 is a circulating adipokine, which is upregulated in obese complications including coronary artery disease. Here, we investigated the role of CTRP1 in regulation of vascular remodeling after mechanical injury and evaluated its potential mechanism. METHODS: Mice were subjected to wire-induced injury...
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