Article
Differences in HIV type 1 RNA plasma load profile of closely related cocirculating Ethiopian subtype C strains: C and C'.
AIDS research and human retroviruses - 1 Jul 2010
Ayele Workenesh, Mekonnen Yared, Messele Tsehaynesh, Mengistu Yohannes, Tsegaye Aster, Bakker Margreet, Berkhout Ben, Dorigo-Zetsma Wendelien, Wolday Dawit, Goudsmit Jaap, Coutinho Roel, de Baar Michel, Paxton William A, Pollakis Georgios
Abstract excerpt
Two HIV-1 subtype C subclusters have been identified in Ethiopia (C and C') with little knowledge regarding their biological or clinical differences. We longitudinally monitored HIV-1 viral loads and CD4(+) T cell counts for 130 subtype C-infected individuals from Ethiopia over 5 years. The genetic subclusters C and C' were determined and comparisons were made between the groups. None of the study individuals...
Topics
- Adult
- CD4 Lymphocyte Count
- Ethiopia
- Female
- Genotype
- HIV Infections
- HIV-1
- Humans
- Longitudinal Studies
- Male