Article
Phylodynamics of HIV-1 subtype C epidemic in east Africa.
PloS one - 1 Jan 2012
Delatorre Edson Oliveira, Bello Gonzalo
Abstract excerpt
The HIV-1 subtype C accounts for an important fraction of HIV infections in east Africa, but little is known about the genetic characteristics and evolutionary history of this epidemic. Here we reconstruct the origin and spatiotemporal dynamics of the major HIV-1 subtype C clades circulating in east Africa. A large number (n = 1,981) of subtype C pol sequences were retrieved from public databases to explore...
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