Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Stromal Fibroblasts from the Interface Zone of Triple Negative Breast Carcinomas Induced Epithelial-Mesenchymal Transition and its Inhibition by Emodin.

PloS one - 1 Jan 2017

Hsu Hsiang-Chi, Liu Liang-Chih, Wang Hao-Yu, Hung Chao-Ming, Lin Ying-Chao, Ho Chi-Tang, Way Tzong-Der

Abstract excerpt

"Triple negative breast cancer" (TNBC) is associated with a higher rate and earlier time of recurrence and worse prognosis after recurrence. In this study, we aimed to examine the crosstalk between fibroblasts and TNBC cells. The fibroblasts were isolated from TNBC patients' tissue in tumor burden zones, distal normal zones and interface zones. The fibroblasts were indicated as cancer-associated fibroblasts...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-Associated Fibroblasts
Share to Cell Line, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epithelial-Mesenchymal Transition

Share to Fibroblasts

Share to Phenotype

Share to Transforming Growth Factor beta

Share to Triple Negative Breast Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 28060811
DOI: 10.1371/journal.pone.0164661
PMCID: PMC5218416

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Stromal Fibroblasts from the Interface Zone of Triple Negative Breast Carcinomas Induced Epithelial-Mesenchymal Transition and its Inhibition by Emodin.PMID 28060811Read ↗

Cancer-associated fibroblasts rewire the estrogen receptor response in luminal breast cancer, enabling estrogen independenceSemantic proximity Read ↗

Stromal-epithelial interactions in breast cancer.Semantic proximity Read ↗

TGF-beta receptor type-2 expression in cancer-associated fibroblasts regulates breast cancer cell growth and survival and is a prognostic marker in pre-menopausal breast cancerSemantic proximity Read ↗

Integration of molecular profiling and chemical imaging to elucidate fibroblast-microenvironment impact on cancer cell phenotype and endocrine resistance in breast cancer.Semantic proximity Read ↗

Understanding the impact of 2D and 3D fibroblast cultures on in vitro breast cancer models.Semantic proximity Read ↗

Lovastatin Inhibits EMT and Metastasis of Triple-Negative Breast Cancer Stem Cells Through Dysregulation of Cytoskeleton-Associated ProteinsSemantic proximity Read ↗

The Effect Of Malignant Breast Tissue Stromal Cells On The Growth Of Cancer Cells And The Relationship Of miRNASemantic proximity Read ↗

The Inhibition of FGFR/PI3K/Akt Axis by AZD4547 Disrupts the Proangiogenic Microenvironment and Vasculogenic Mimicry Arising from the Interplay between Endothelial and Triple-Negative Breast Cancer CellsSemantic proximity Read ↗

Cancer-Associated Fibroblasts Autophagy Enhances Progression of Triple-Negative Breast Cancer CellsSemantic proximity Read ↗

Cancer-associated fibroblasts release exosomal microRNAs that dictate an aggressive phenotype in breast cancer.Semantic proximity Read ↗

Preconditioned Chorionic Villus Mesenchymal Stem/Stromal Cells (CVMSCs) Minimize the Invasive Phenotypes of Breast Cancer Cell Line MDA231 In Vitro.Semantic proximity Read ↗

Cross-talk of EGF and IGF-1 signaling promotes EMT gene expression: Implications for morphology and proliferation in breast cancer cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.