Article
Transstadial Transmission and Long-term Association of Crimean-Congo Hemorrhagic Fever Virus in Ticks Shapes Genome Plasticity.
Scientific reports - 24 Oct 2016
Xia Han, Beck Andrew S, Gargili Aysen, Forrester Naomi, Barrett Alan D T, Bente Dennis A
Abstract excerpt
The trade-off hypothesis, the current paradigm of arbovirus evolution, proposes that cycling between vertebrate and invertebrate hosts presents significant constraints on genetic change of arboviruses. Studying these constraints in mosquito-borne viruses has led to a new understanding of epizootics. The trade-off hypothesis is assumed to be applicable to tick-borne viruses too, although studies are lacking....
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