Comparison of Clinically Relevant Mutation Profiles Between Preoperative Biopsy and Corresponding Surgically Resected Specimens in Japanese Patients With Non-Small-cell Lung Cancer by Amplicon-based Massively Parallel Sequencing.

doi:10.1016/j.cllc.2016.11.022

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Comparison of Clinically Relevant Mutation Profiles Between Preoperative Biopsy and Corresponding Surgically Resected Specimens in Japanese Patients With Non-Small-cell Lung Cancer by Amplicon-based Massively Parallel Sequencing.

Clinical lung cancer - 1 Sept 2017

Isaka Mitsuhiro, Serizawa Masakuni, Kenmotsu Hirotsugu, Koh Yasuhiro, Takahashi Shoji, Maniwa Tomohiro, Wakuda Kazushige, Ono Akira, Naito Tateaki, Murakami Haruyasu, Mori Keita, Endo Masahiro, Abe Masato, Hayashi Isamu, Nakajima Takashi, Yamamoto Nobuyuki, Takahashi Toshiaki, Ohde Yasuhisa

Abstract excerpt

BACKGROUND: Amplicon-based massively parallel sequencing (MPS) is an effective platform for identifying clinically actionable mutations across many genes in limited amounts of tissue. Most lung cancers are diagnosed and staged using small tissue samples obtained by transbronchial biopsy (TBB). To determine whether the mutations in TBB specimens detected by amplicon-based MPS reflect those present in the tumors,...

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PMID: 28057436
DOI: 10.1016/j.cllc.2016.11.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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