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Article

Genomic analysis of exceptional responders to radiotherapy reveals somatic mutations in ATM.

Oncotarget - 7 Feb 2017

Ma Jennifer, Setton Jeremy, Morris Luc, Albornoz Pedro Blecua Carrillo, Barker Christopher, Lok Benjamin H, Sherman Eric, Katabi Nora, Beal Kathryn, Ganly Ian, Powell Simon N, Lee Nancy, Chan Timothy A, Riaz Nadeem

Abstract excerpt

Radiation therapy is a mainstay of cancer treatment, yet the molecular determinants of clinical response are poorly understood. We identified exceptional responders to radiotherapy based on clinical response, and investigated the associated tumor sequencing data in order to identify additional patients with similar mutations. Among head and neck squamous cell cancer patients receiving palliative radiotherapy at...

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Share to Ataxia Telangiectasia Mutated Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28055970
DOI: 10.18632/oncotarget.14400
PMCID: PMC5354661

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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