Article
Association of potentially functional variants in the XPG gene with neuroblastoma risk in a Chinese population.
Journal of cellular and molecular medicine - 1 Aug 2016
He Jing, Wang Fenghua, Zhu Jinhong, Zhang Ruizhong, Yang Tianyou, Zou Yan, Xia Huimin
Abstract excerpt
XPG gene plays a critical role in the nucleotide excision repair pathway. However, the association between XPG gene polymorphisms and neuroblastoma risk has not been investigated. In this study with 256 neuroblastoma cases and 531 cancer-free controls, we investigated the effects of five potentially functional polymorphisms (rs2094258 C>T, rs751402 C>T, rs2296147 T>C, rs1047768 T>C and rs873601G>A) on...
Read the complete abstract on PubMed