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Article

NLRP3 inflammasome activation contributes to aldosterone-induced podocyte injury.

American journal of physiology. Renal physiology - 1 Apr 2017

Bai Mi, Chen Ying, Zhao Min, Zhang Yue, He John Ci-Jiang, Huang Songming, Jia Zhanjun, Zhang Aihua

Abstract excerpt

Aldosterone (Aldo) has been shown as an important contributor of podocyte injury. However, the underlying molecular mechanisms are still elusive. Recently, the pathogenic role of NOD-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome in mediating renal tubular damage was identified while its role in podocyte injury still needs evidence. Thus the present study was undertaken to investigate the...

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Source

Identifiers

PMID: 28052869
DOI: 10.1152/ajprenal.00332.2016

Genes

NLRP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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