Article
Pregnancy-related changes of antiretroviral pharmacokinetics: an argument for therapeutic drug monitoring.
Antiviral therapy - 1 Jan 2017
Simonetti Francesco R, Cattaneo Dario, Zanchetta Nadia, Giacomet Vania, Micheli Valeria, Ciminera Nadia, Gervasoni Cristina
Abstract excerpt
Here we describe a case of an HIV-infected young woman with extensive drug-resistant virus, who was successfully switched from a raltegravir-based regimen to a dolutegravir-based intensified antiretroviral regimen a few days before scheduled caesarean section because of the still detectable viral load. The trough concentrations of all antiretroviral drugs before and after delivery are also described. Our case...
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