Article
Reciprocal signaling by Wnt and Notch specifies a muscle precursor in the C. elegans embryo.
Development (Cambridge, England) - 1 Feb 2017
Robertson Scott M, Medina Jessica, Oldenbroek Marieke, Lin Rueyling
Abstract excerpt
The MS blastomere produces one-third of the body wall muscles (BWMs) in the C. elegans embryo. MS-derived BWMs require two distinct cell-cell interactions, the first inhibitory and the second, two cell cycles later, required to overcome this inhibition. The inductive interaction is not required if the inhibitory signal is absent. Although the Notch receptor GLP-1 was implicated in both interactions, the molecular...
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