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Article

Chrna7 deficient mice manifest no consistent neuropsychiatric and behavioral phenotypes.

Scientific reports - 3 Jan 2017

Yin Jiani, Chen Wu, Yang Hongxing, Xue Mingshan, Schaaf Christian P

Abstract excerpt

The alpha7 nicotinic acetylcholine receptor, encoded by the CHRNA7 gene, has been implicated in various psychiatric and behavioral disorders, including schizophrenia, bipolar disorder, epilepsy, autism, Alzheimer's disease, and Parkinson's disease, and is considered a potential target for therapeutic intervention. 15q13.3 microdeletion syndrome is a rare genetic disorder, caused by submicroscopic deletions on...

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Identifiers

PMID: 28045139
DOI: 10.1038/srep39941
PMCID: PMC5206704

Genes

CHRNA7

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