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Article

The human clinical phenotypes of altered CHRNA7 copy number.

Biochemical pharmacology - 15 Oct 2015

Gillentine Madelyn A, Schaaf Christian P

Abstract excerpt

Copy number variants (CNVs) have been implicated in multiple neuropsychiatric conditions, including autism spectrum disorder (ASD), schizophrenia, and intellectual disability (ID). Chromosome 15q13 is a hotspot for such CNVs due to the presence of low copy repeat (LCR) elements, which facilitate non-allelic homologous recombination (NAHR). Several of these CNVs have been overrepresented in individuals with...

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Source

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Identifiers

PMID: 26095975
DOI: 10.1016/j.bcp.2015.06.012
PMCID: PMC4600432

Genes

CHRNA7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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