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Article

Aberrant promoter methylation of hOGG1 may be associated with increased risk of non-small cell lung cancer.

Oncotarget - 31 Jan 2017

Qin Hualong, Zhu Jianjie, Zeng Yuanyuan, Du Wenwen, Shen Dan, Lei Zhe, Qian Qian, Huang Jian-An, Liu Zeyi

Abstract excerpt

DNA methylation may epigenetically inactivate tumor suppressor genes in NSCLC. As the human 8-oxoguanine DNA glycosylase (hOGG1) gene promoter is frequently methylated in NSCLC, we evaluated whether genetic or epigenetic alterations of hOGG1 are associated with increased risk of non-small cell lung cancer. Three hOGG1 haplotype-tagging SNPs (htSNP) were genotyped in PCR-restriction fragment length polymorphism...

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Identifiers

PMID: 28039450
DOI: 10.18632/oncotarget.14177
PMCID: PMC5352404

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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