Article
Association of polymorphisms in pharmacogenetic candidate genes (OPRD1, GAL, ABCB1, OPRM1) with opioid dependence in European population: a case-control study.
PloS one - 1 Jan 2013
Beer Beate, Erb Robert, Pavlic Marion, Ulmer Hanno, Giacomuzzi Salvatore, Riemer Yvonne, Oberacher Herbert
Abstract excerpt
It is becoming increasingly evident that genetic variants contribute to the development of opioid addiction. An elucidation of these genetic factors is crucial for a better understanding of this chronic disease and may help to develop novel therapeutic strategies. In recent years, several candidate genes were implicated in opioid dependence. However, most study findings have not been replicated and additional...
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