Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide quantitative trait loci mapping of the human cerebrospinal fluid proteome.

Human molecular genetics - 1 Jan 2017

Sasayama Daimei, Hattori Kotaro, Ogawa Shintaro, Yokota Yuuki, Matsumura Ryo, Teraishi Toshiya, Hori Hiroaki, Ota Miho, Yoshida Sumiko, Kunugi Hiroshi

Abstract excerpt

Cerebrospinal fluid (CSF) is virtually the only one accessible source of proteins derived from the central nervous system (CNS) of living humans and possibly reflects the pathophysiology of a variety of neuropsychiatric diseases. However, little is known regarding the genetic basis of variation in protein levels of human CSF. We examined CSF levels of 1,126 proteins in 133 subjects and performed a genome-wide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Genome, Human

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Mental Disorders

Share to Protein Array Analysis

Share to Proteome

Share to Proteomics

Share to Quantitative Trait Loci

Source

Identifiers

PMID: 28031287
DOI: 10.1093/hmg/ddw366

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide quantitative trait loci mapping of the human cerebrospinal fluid proteome.PMID 28031287Read ↗

Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and informs causal proteins for Alzheimer’s diseaseSemantic proximity Read ↗

TOPMed imputed genomics enhances genomic atlas of the human proteome in brain, cerebrospinal fluid, and plasma.Semantic proximity Read ↗

Genomic and multi-tissue proteomic integration for understanding the biology of disease and other complex traitsSemantic proximity Read ↗

Genomic and multi-tissue proteomic integration for understanding the biology of disease and other complex traitsSemantic proximity Read ↗

Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and implicates causal proteins for Alzheimer's disease.Semantic proximity Read ↗

Mapping the serum proteome to neurological diseases using whole genome sequencing.Semantic proximity Read ↗

Genetic regulation of human brain proteome reveals proteins implicated in psychiatric disordersSemantic proximity Read ↗

Genetic regulation of human brain proteome reveals proteins implicated in psychiatric disorders.Semantic proximity Read ↗

Genetic mechanisms of 184 neuro-related proteins in human plasmaSemantic proximity Read ↗

Characterizing the impact of plasma protein levels on human brain structure and disorders leveraging integrative multi-omics analysisSemantic proximity Read ↗

Colocalization and discordance between plasma and brain protein quantitative trait lociSemantic proximity Read ↗

Unraveling Neuro-Proteogenomic Landscape and Therapeutic Implications for Human Behaviors and Psychiatric DisordersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.