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Article

TOPMed imputed genomics enhances genomic atlas of the human proteome in brain, cerebrospinal fluid, and plasma.

Scientific data - 16 Apr 2024

Yi Heng, Yang Qijun, Repaci Charlie, Lee Cheolmin Matthew, Heo Gyujin, Timsina Jigyasha, Gorijala Priyanka, Yang Chengran, Budde John, Wang Lihua, Cruchaga Carlos, Sung Yun Ju

Abstract excerpt

Comprehensive expression quantitative trait loci studies have been instrumental for understanding tissue-specific gene regulation and pinpointing functional genes for disease-associated loci in a tissue-specific manner. Compared to gene expressions, proteins more directly affect various biological processes, often dysregulated in disease, and are important drug targets. We previously performed and identified...

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Source

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Identifiers

PMID: 38627416
DOI: 10.1038/s41597-024-03140-3
PMCID: PMC11021418

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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