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Article

The role of miR-17-92 in the miRegulatory landscape of Ewing sarcoma.

Oncotarget - 14 Feb 2017

Schwentner Raphaela, Herrero-Martin David, Kauer Maximilian O, Mutz Cornelia N, Katschnig Anna M, Sienski Grzegorz, Alonso Javier, Aryee Dave N T, Kovar Heinrich

Abstract excerpt

MicroRNAs serve to fine-tune gene expression and play an important regulatory role in tissue specific gene networks. The identification and validation of miRNA target genes in a tissue still poses a significant problem since the presence of a seed sequence in the 3'UTR of an mRNA and its expression modulation upon ectopic expression of the miRNA do not reliably predict regulation under physiological conditions....

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Topics

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Share to 3' Untranslated Regions
Share to Bone Morphogenetic Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Oncogene Proteins, Fusion

Share to Proto-Oncogene Protein c-fli-1

Share to RNA-Binding Protein EWS

Share to RNA, Long Noncoding

Share to Sarcoma, Ewing

Share to Sequence Analysis, RNA

Source

Open in PubMed Open full text

Identifiers

PMID: 28030800
DOI: 10.18632/oncotarget.14091
PMCID: PMC5355239

Genes

FLI1
AGO2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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