Article

BMPR1A signalling is linked to tumour progression in dedifferentiated liposarcomas: lessons for rhBMP2 use in spinal surgery

2016-02-06

Abstract excerpt

Bone Morphogenic Protein 2 (BMP2) is a multipurpose cytokine, important in the development of bone and cartilage, and with a role in tumour initiation and progression. Because of BMP2’s osteogenic properties, a recombinant human version (rhBMP2) has found utility as an adjuvant therapy during surgery for spinal fusions. However, the results of large-scale meta-analysis has highlighted the potential of rhBMP2 to pr...

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Literature Corpus work: 1c641d46-ace4-5698-aecf-b3a698cee687
DOI: 10.7287/peerj.preprints.1719v1

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