Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional, chemical genomic, and super-enhancer screening identify sensitivity to cyclin D1/CDK4 pathway inhibition in Ewing sarcoma

18 Aug 2015

Abstract excerpt

// Alyssa L. Kennedy 1, 2, * , Mounica Vallurupalli 1, 3, * , Liying Chen 1, * , Brian Crompton 1 , Glenn Cowley 4 , Francisca Vazquez 4 , Barbara A. Weir 4 , Aviad Tsherniak 4 , Sudha Parasuraman 5 , Sunkyu Kim 5 , Gabriela Alexe 1, 4, 6 , Kimberly Stegmaier 1, 4 1 Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children’s Hospital, Boston, Massachusetts, USA 2 Boston Combined Residency...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Lymphoma Diagnosis and Treatment
Share to RNA modifications and cancer
Share to Sarcoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26337082
DOI: 10.18632/oncotarget.4903

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional, chemical genomic, and super-enhancer screening identify sensitivity to cyclin D1/CDK4 pathway inhibition in Ewing sarcomaPMID 26337082Read ↗

Super-enhancer-associated MEIS1 promotes transcriptional dysregulation in Ewing sarcoma in co-operation with EWS-FLI1Semantic proximity Read ↗

Epigenetic and Transcriptional Signaling in Ewing Sarcoma—Disease Etiology and Therapeutic OpportunitiesSemantic proximity Read ↗

Robust diagnosis of Ewing sarcoma by immunohistochemical detection of super-enhancer-driven EWSR1-ETS targetsSemantic proximity Read ↗

Oncofusion-driven <i>de novo</i> enhancer assembly promotes malignancy in Ewing sarcoma <i>via</i> aberrant expression of the stereociliary protein LOXHD1Semantic proximity Read ↗

Reversible LSD1 Inhibition Interferes with Global EWS/ETS Transcriptional Activity and Impedes Ewing Sarcoma Tumor GrowthSemantic proximity Read ↗

Systematic multi-omics cell line profiling uncovers principles of Ewing sarcoma fusion oncogene-mediated gene regulationSemantic proximity Read ↗

cIAP1 inhibitor of apoptosis is a tumor suppressor in Ewing sarcomaSemantic proximity Read ↗

Oncofusion-driven de novo enhancer assembly promotes malignancy in Ewing sarcoma via aberrant expression of the stereociliary protein LOXHD1Semantic proximity Read ↗

Ewing and Ewing-like-sarcoma tumoroid biobank reveals distinct drug sensitivities: translocation makes the differenceSemantic proximity Read ↗

NSMCE2, a Novel Super-Enhancer-Regulated Gene, is Linked to Poor Prognosis and Therapy Resistance in Breast CancerSemantic proximity Read ↗

Ewing sarcoma fusion oncogene: At the crossroads of transcription and DNA damage responseSemantic proximity Read ↗

Oncogenic super-enhancer formation in tumorigenesis and its molecular mechanisms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.