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CSF3R, SETBP1 and CALR mutations in chronic neutrophilic leukemia

14 Oct 2014

Abstract excerpt

The WHO 2008 definition of chronic neutrophilic leukemia (CNL) is based on clinical and laboratory parameters but not on molecular abnormalities. Mutations in CSF3R, SETBP1 and CALR are reported in patients with chronic neutrophilic leukemia (CNL). However, because CNL is rare, there are few large studies of this issue. We sequenced these genes in 14 patients who met the WHO-criteria of CNL. 8 subjects had...

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PMID: 25316523
DOI: 10.1186/s13045-014-0077-1

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