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Article

Global methylation of blood leukocyte DNA and risk of melanoma.

International journal of cancer - 1 Apr 2017

Shen Jie, Song Renduo, Wan Jie, Huff Chad, Fang Shenying, Lee Jeffrey E, Zhao Hua

Abstract excerpt

Global DNA methylation, possibly influenced by lifestyle and environmental factors, has been suggested to play an active role in carcinogenesis. However, its role in melanoma has rarely been explored. The aims of this study were to evaluate the relationship between melanoma risk and levels of 5-methylcytosine (5-mC), a marker for global DNA methylation, in blood leukocyte DNA, and to determine whether this 5-mC...

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Identifiers

PMID: 28006848
DOI: 10.1002/ijc.30577
PMCID: PMC5630148

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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